Lung cancer in never smokers (LCINS): development of a UK national research strategy

Khan, S, Hatton, N, Tough, D., Rintoul, R.C, Pepper, C, Calman, L, McDonald, F, Harris, C, Randle, A, Turner, M.C, Haley, R.A, Rawlinson, J, Crosbie, P.A.J, McCaughan, F and Hatton, M (2023) Lung cancer in never smokers (LCINS): development of a UK national research strategy. BJC Reports, 2 (1). pp. 1-9. ISSN 2731-9377

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Introduction Lung cancer in never smokers (LCINS) accounts for 15% of lung cancers diagnosed in the UK, making it the 8th most common cancer. There are few robust studies specific to the LCINS population making data surrounding the incidence and mortality of LCINS incomplete, leaving many gaps in our understanding of the needs of this population. Methods To address a lack of research in this important area, the UK National Cancer Research Institute Lung Study Group (NCRI-LSG) undertook a national survey and hosted a research strategy day to define key research priorities. A wide cross section of stakeholders, including patient advocates, the charitable sector, basic and translational researchers, and multi-disciplinary healthcare professionals contributed highlighting their research priorities. Results One-hundred twenty-seven surveys were completed (52 by patients/patient advocates) prior to the strategy day. These identified themes for expert review presentations and subsequent workshop discussions at the national research strategy day, which registered 190 attendees (50 patients/patient advocates). The four key themes that emerged to form the basis of a research strategy for LCINS are (1) Raising awareness, (2) Risk assessment and early detection, (3) Disease biology, (4) Living with and beyond. Conclusion This paper summarises current evidence and important gaps in our knowledge related to LCINS. We present recommendations for a national research strategy aimed at improving outcomes for patients.

Item Type: Article
Additional Information: © 2023 Nature. This is an author accepted manuscript of a paper subsequently published in BJC Reports. Uploaded in accordance with the publisher's self-archiving policy.
Depositing User: Daniel Tough
Date Deposited: 31 Jul 2023 08:50
Last Modified: 31 Jul 2023 08:50

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